FOXO4-DRI
Also known as: FOXO4 D-Retro-Inverso peptide
Summary
An experimental senolytic peptide studied for selectively clearing senescent cells.
How it works
Disrupts the FOXO4–p53 interaction in senescent cells, triggering their apoptosis while sparing healthy cells in preclinical models.
What it’s studied for
- Studied as a senolytic in animal models
- Reported improvements in markers of ageing in mice
- Investigated for tissue-function research
Research-reported protocol
Only animal-study dosing exists; there is no established human protocol.
Route: Injectable (research only). These are amounts described in the research literature — not an instruction to administer anything.
Reconstitution — run the numbers
The same calculator the coach uses. Enter a vial size, water, and a dose to see the exact draw on a U-100 syringe.
Reconstitution
live · real mathDraw to
on a U-100 syringe
10units
2,500
mcg/mL
0.1
mL/dose
20
doses/vial
Show the math
- Concentration2,500 mcg/mL
vial mg ÷ water mL × 1,000
5 mg ÷ 2 mL × 1,000
- Volume per dose0.1 mL
dose mcg ÷ concentration
250 mcg ÷ 2,500 mcg/mL
- Units to draw10 units
mL per dose × 100
0.1 mL × 100
- Doses per vial20 doses
vial mcg ÷ dose mcg (rounded down)
5,000 mcg ÷ 250 mcg
Calculated, not guessed — the same math the app and coach use. Double-check it yourself.
The exact math, shown in the open. Full tool at the calculator.
Cautions
- No human safety data
- Highly experimental; a research chemical not approved for human use
Evidence & sources
Written by Titria Research Team.
A credentialed reviewer (PhD/PharmD) and a primary-literature citation list are still being added — we show this state honestly rather than implying a review that hasn’t happened. It means the sign-off is pending, not that the entry is unsupported. See how we rate evidence.
Check the primary literature yourself — testing our labels is encouraged.
Often studied alongside
Model a FOXO4-DRI protocol for your goals.
The coach interviews you, grounds every dose in this database and the calculator above, and saves a research protocol — never a hallucinated number.